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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c62de7b2c1987fbd0df06d733f6938e6986a128e3cf9b3b7646b5a32b86afe6' 
  AND token = '+W4L6cfFWmvMETFCV3IGPnTtpbBCkwKkgWFwmLjsKlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}