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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b25ad48bdb50a559a050cea7b53a7fa8e5340aa54f5c9a697dec2069e60e2a' 
  AND token = 'cbBUn+ErCMzn7D5QLLcWLk0I1C0NgbPosNayYwSFLFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}