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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3270a1ae9a8f1c460107b4e08e9402e879ded3344841261e33397e92e2f2e1b' 
  AND token = 'JWUO95CyHl2R0S6Nq64ZEJJMTrEaX+1IlObDqXBvBmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}