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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ea3ddf1ee1625d186a83ee3f6c9b7df789d9ce595125b02039be82d5323e16f' 
  AND token = '+NQ82+YboPafBXkND64U2IfjNudsTjg99mXUPc9KPck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}