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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd722e2f4c36e475b303da4582359554a0d6c74054cb5cd3a6201425939f1d4bb' 
  AND token = '3ZX3ZFbZI5/8X5OfjixfM0+Ytj2/mCRYS5mx73XrYdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}