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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5959ccd11123029af5488a74bee2fa012db0c2ec20b5f47d674d476979cb1d1f' 
  AND token = 'bL7Gtn63otkiPE7HnH/t3nvap6HS2qIAYGdM6N+7cmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}