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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6292c2acffd0cd01c6adbd931764476f56391250d44d398ae248160103c0e1a' 
  AND token = 'lCCEdZ+czZ+yDWSvMyGVS8HUT5HIt2QQamQh9Vd9WBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}