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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '625311a164a6b251b4e7d2682f7f48ec38bce5f62885f260c97112505704e4c4' 
  AND token = 'rbLChoUg9Ngo6bON88qAR2UeMoH5ekq7otdA+u2F8Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}