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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '077b8183c0bb92f534d9bfc184984bcde25ff9e5380eb4e575f852afe6f9cd47' 
  AND token = 'Fd7aaP6tnfEP9MNkxnB/LVlPmHScmXAGsuxHdzuY5q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}