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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '316b9e6f924b4f897553a4c2484deb241baa6e2ac195ac6e0a65d96a59b44ffc' 
  AND token = 'E/Kb4Gdtgio/OT0fLvIp6tQm6IrxKxI9QPseJo5x7XY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}