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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd505d4b10df7fdd61aeb42e6a53a54902eb29647208ab70341d0ebbe9618ecd' 
  AND token = 'wfJsNeyS9kIQx5fLn7mS+CSkSm/6dCmZZjMF5qBA7jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}