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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd64e5704445592ef6cfaa351a2d6f5b9559811741dec90bcd1d527380c3c9888' 
  AND token = 'Gh6XT7XCkrYQ2lDTFisCU1uQI9752NEFY/Z6CPC4WPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}