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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e823b9e8aa9d41a22cd0f96101618002ba1f9e2682d19822c4016cc79c16842' 
  AND token = '/PvEzK7DF4HZH+pAH9f4iFlMtZQYyHFscWnFWrrq5so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}