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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1904e7e136dcd0f2a93bac7440e164643382281b3f6d767f5a57316337dc4bb1' 
  AND token = 'I1Etm1joKNQC6RX385c0vYtRMQ7fCRCA385bbBvIVro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}