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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66d18f6d2982e7d5f777c6698e52a83844535192b68251b3e3daa4e928c031d2' 
  AND token = 'w+ONkkb3CAcLJvq8drOKjAkVyyD5UF1yzqulbBA1l4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}