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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4528651e7d8c0ccb9dad9b32a466bed7e7f339dd0ef43fab2072ba23881ea8a' 
  AND token = 'e4E5cNli99OvvGxs+We+4Yx9E0cM8jiWzM3+IvkELDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}