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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '710ee317a80b41a1c68700bd79ab8a227f017d5d2c76f691fb6023934c7e868b' 
  AND token = 'JeO1SfYparrbCA60Wpd/mOnPLVLqJTpzDyfXDfj85hU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}