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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3af30f76586b1cfdce16528f33117b250cb3d38afebdd5ae128f9f5f5918f69d' 
  AND token = 'Uxa4tGMpA55ha1f72SqaAKIr43aEW0WN2RcndXGkeuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}