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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd362714989250887f6381bac4d01d57c64c1f6865cf772bd5769d8541d13cb37' 
  AND token = 'MOD4NXAg+GVMftV8YZjpnHpudOHSJ3ydg6nHq2rU7Ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}