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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b4b3a317455905f7c84fa0052fa863a4ff9cca27b16b3a39426999f48398121' 
  AND token = '7uMJgNO04DDoiY4bPeeHu4EdSFlIMY0jAo+0GZJcVIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}