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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d502096dd9c29292d35a26dcf704da94713deb88e6f4af43ac3316fd12cbc0' 
  AND token = 'EtFNG/U1Og326LZcGxlS13osnwAqC++dXj3C6HxbrOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}