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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e11558f04ea55ca4a9a223bfbb97084350347c8b91903d5afb334dcfe064f5' 
  AND token = '1mlbJAjZ/3TXFdl5nyP9gSSztngN5z41a1NCbPcHkeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}