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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df0f4b9e4637504684f0448901ee4c4dc2e3799e9602b2db992a8c2b2602dd96' 
  AND token = 'SOTfBkb3+uDkWHPK8k8mGzW+Zo1JfAqgC+fBsJyaiKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}