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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048b045605e7ff5ec21e29debe2a12b530679e828eb9a9273083d4150c392844' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}