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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38c685d463f08a877deb8e472aa343cbfa00b499f51c54ab2cb9b273ae2c2388' 
  AND token = 'HCVMwMcW9+rjon6NpOmL7tWrWThz3IyHZHyuvgX5lno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}