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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '234f651c4631c295a7acb1d99bbcfb23c5bd78aeed0d3ec0b4c0ea142edfcca0' 
  AND token = 'udpV4OGrTUVlITrE4EnYv2XJsTpjpoFENXlzoJ5dOs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}