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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c3fc9653e8bd5d6b224869656de06281eab1384cf92bfa1a23c73b6caffaf8e' 
  AND token = 'OIVOA1gdLODHQN0fwuV1Xk6pHLqdBHk9QpRTqluEBY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}