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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6750039dc9ad319e5f2818efcf0db8b7d18377a3f9c14408538bbd7ccd76227' 
  AND token = 'KVTbIgIMGi4atI6+uuK2q33xRbgmw6kG687GM5KDqnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}