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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c81b2dffe787a77c22186e3e6515c143667f48b07b61b0ec1822d15ee9c6d5d' 
  AND token = 'yX66RDv+gZQ2S16oHwGkFKyBtAs9BCS8g0962GWjBiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}