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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e115b4a69b4962cef2a3a07a08405e6339753c1310674a7f4d19e10673e6b4fa' 
  AND token = 'FtwQcJCD2UyvV/wBdaNDNfves/BK9RP3tTWhp1obGpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}