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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8b1ec50ea52edbfe87933286b0d881495f8dd9f6f54485859842a64a28d934e' 
  AND token = 'I/YQdim7+kNbW24/Q8llpKQkogQBcUE3Mn9tux92ebc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}