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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1720b208b103516559b8789efdd8806c5febd1487ec18d70cb9c71e67996f2c7' 
  AND token = 'UcTrcGWbLQYQgv4WeOYkxnH02x2WMVxb3qLt2fD47VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}