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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e6d1495e54be65613b63ee758f345ac373b0bcf4d46e50cca73d5446c18bd96' 
  AND token = '20LOx3NeWElsLZ1wwG+1yZNyt8su1YFR8EP80/Uc2CQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}