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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb9bb71d27aed83966126c44f8132aa88b9a2acd3d849e24d099c5ba3c9df504' 
  AND token = '20KM/cEDmOcj+o3IycvbVlp1wklPKkE0CDTZUm5Sgf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}