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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5906e4721411a41ad167eac4c9c32fb1d85a0b0eefdcc850e86b5d8db98b96a5' 
  AND token = 'ZZ5+xHo4aP4KZtlb7hW9OGv5k7Q9kH1TB2zGA6jFR08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}