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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8b0d407fb3e1e54b2706a39257695666c5b304c121a1872b62bf786cb1ce3c7' 
  AND token = 'I5UlvSZeQJ00lPTUtPkAH5SRS2AclmE07hR1URqU+oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}