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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c5bc058c98b6751cf07e7ed3b5c6937dbfefeccc046b10039ad9afe960ee0b2' 
  AND token = 'U1Y54XgJWulGRc+J/FgEcqKWBIzK9qMbEXsXsKV2K8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}