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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4437a124fcf4492285e25633d04a48d1d035a64c0071529e0a10cb6ccf2b0ed' 
  AND token = 'EJLpa+u2GpMNipmXh6RtpamcNQ2M1TMKbfDSEDncM6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}