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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50f92808a843078ff2ead56724097755d4617f3481c029907b29261e08517b9' 
  AND token = 'QtjNRt60IL/ZJOA7ALAD6Yuh0pTD6A05d1FnL9s6Ztw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}