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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cea91641bb5b2375bfcf52eaa95a894a7de872f9789a073b7aa8925ba897f64' 
  AND token = 'QW+v2CreRzbsA2Z1QEpdFsuHUv67Ff096R1Jpmk8Qes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}