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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6489fb95e6a05816e6f5f0fdc29b084d8e41375543f1908852bd833c72c48754' 
  AND token = 'P7qfPqkPdgEiQxiM9fwwF+uOFyaZ9pkfBIo7NI2Pf3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}