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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f465ef464ffc5eedbc8b33c57dfdad473dbb3ad85f0bb3cef56ca550f66e6380' 
  AND token = 'm64zdUmxuVvjxr/VZaEgoOU9h16yfUewjMgN10eDmuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}