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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc9500e430d61fe1e9a3a091e10e694abc06626f1dda51263c31f373f4ceb7b' 
  AND token = 'q9IwsKI7Tg1271FV/x+Tkpt44lFNHkGfxdOYTyH01kI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}