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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3257c90ae3de170e6e57ca9033354a520cf868296c9d5d1ef8f11acee3a0d85b' 
  AND token = 'TvkmDdTIpZeTjSwXeOEZSY/vtBljwblm0khT57soOAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}