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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6172ca3af1fdb7adc3cacef2f5f5ccdce27f354b2364d7cd111e778b50b866b' 
  AND token = 'XAQnOpjiCLK4WCMFeBJY2sLBGVDw6pR8NiMfCGDjykI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}