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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0e04eed7836028a41b7e3d9643a1fcb6b4c0e1530705e581c3f2d879683b25' 
  AND token = 'nMfaNS/zsyqbpKeWSijhIZItkXw4BFHiLmpxtM2NcYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}