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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa4e604988c3eda3c3bb72e4ea433b47afbee6e2ef7519ec0db9f548ae1c4297' 
  AND token = 'FdY/x5qm26LYF8nhp3WrvJ20VVyfUFCjt1HFmdgPlnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}