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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57dc1d173804f8f1011868431b7207422311158080be9c05917dccc6e9d96b29' 
  AND token = '0yYl+ZhxqHI577tNtZUYnXllrJvwx4LQ9kIGI533wS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}