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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2ddb9d51971bc7578c1f7e7c9326369cda68614b401219a2b6c24a50469ba13' 
  AND token = 'N4Vnq1UlxyeAkgA4NNfYfCArCzhA3RTYhWj4DnMozK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}