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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd07810626125b787294bb2455cb2ec396a14316daf2202617d4ad6f8288620b1' 
  AND token = 'qVAoIV1222YjAYoXFZPNfnsMzMkJGRvPQbAhhFne0zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}